Smart adaptive fluorescence microscopy
Themes: Software technology & Intelligent Systems, Life Science & Health
Late lab scale demonstration
A TRL is a measure to indicate the matureness of a developing technology. When an innovative idea is discovered it is often not directly suitable for application. Usually such novel idea is subjected to further experimentation, testing and prototyping before it can be implemented. The image below shows how to read TRL’s to categorise the innovative ideas.
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Why?
Confocal fluorescence microscopy is a common imaging technique in biological research. Aberrations cause imperfections in the imaging process, limiting its resolution and sensitivity. Smart adaptive optics can correct these aberrations.
How?
We develop hard- and software to create a cost-effective, user-friendly, real-time adaptive microscopy system. The system enables imaging in thicker samples and has a superior resolution.
When?
A successful proof of concept system has been constructed and validated, already allowing for seamless image optimisation without intervention of the user. In the next years an open source system will be developed.
Dean Wilding MRes