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MAiA

Introduction MAIA is an algorithm to integrate multiple genome assemblies. For example, assemblies originating from: Different runs of a de…

Software

Peacock (2017): Phylogenies Visualization library PEDCA (2017): Ploidy Estimation by Dynamic Coverage Analysis GenomeTools (2017):…

Computational Neurobiology

The immense complexity of the mammalian brain is largely reflected in the underlying molecular signatures of its billions of cells. Brain…

Single-cell omics

The most recent breakthrough in genomics is the ability to measure within single cells. Data from hundred thousands, even millions of cells,…

Functional genomics

The central dogma, first posed by Francis Crick in 1958, tells that DNA encodes for Genes which are translated into Proteins. Over the last…

Aging research

Why do some people reach the age of 100 in a healthy condition with no signs of neurodegeneration while others do not. DBL investigates…

Microbial genomics

Microbes are pervasive in all aspects of life, society and industry. We are particularly interested in the effects of genotypes on…

Genome and transcriptome assembly

Genome and transcriptome assembly Two of our most powerful tools to measure biological processes and the organisms involved are DNA- and…

Pangenomes

Sequence graphs are a intuitive way to represent the variation in a collection of DNA sequence. Sets of sequences scale from homologous…

IO bachelor: alumni gezocht!

Als IO-alumni weten jullie als geen ander hoe het is om te ontwerpen en in de echte wereld. We willen jullie perspectief inbrengen in het…