Safety is becoming increasingly relevant in various fields. The renewed focus on Safe by Design (SbD) tries to identify and include safety (along with other important values such as sustainability, security, and circularity) at an early stage of design. Each year we offer PhD course that offers a general outlook on SbD, then dives into different disciplinary perspectives on SbD and its industrial applications and ends with (ethical) reflections on SbD. The team of lecturers encompasses both more academic and more practice-oriented people from TU Delft, WUR, and the National Institute for Public Health and the Environment (RIVM). Group assignments and networking are an important part of the set-up of this course.