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MAiA
Introduction MAIA is an algorithm to integrate multiple genome assemblies. For example, assemblies originating from: Different runs of a de…
Software
Peacock (2017): Phylogenies Visualization library PEDCA (2017): Ploidy Estimation by Dynamic Coverage Analysis GenomeTools (2017):…
Computational Neurobiology
The immense complexity of the mammalian brain is largely reflected in the underlying molecular signatures of its billions of cells. Brain…
Single-cell omics
The most recent breakthrough in genomics is the ability to measure within single cells. Data from hundred thousands, even millions of cells,…
Functional genomics
The central dogma, first posed by Francis Crick in 1958, tells that DNA encodes for Genes which are translated into Proteins. Over the last…
Aging research
Why do some people reach the age of 100 in a healthy condition with no signs of neurodegeneration while others do not. DBL investigates…
Microbial genomics
Microbes are pervasive in all aspects of life, society and industry. We are particularly interested in the effects of genotypes on…
Genome and transcriptome assembly
Genome and transcriptome assembly Two of our most powerful tools to measure biological processes and the organisms involved are DNA- and…
Pangenomes
Sequence graphs are a intuitive way to represent the variation in a collection of DNA sequence. Sets of sequences scale from homologous…
IO bachelor: alumni gezocht!
Als IO-alumni weten jullie als geen ander hoe het is om te ontwerpen en in de echte wereld. We willen jullie perspectief inbrengen in het…