Z. (Ze) Yu
Z. (Ze) Yu
Contact
Profiel
Projecten
Delivering beneficial macromolecules across the cellular membrane is a significant challenge since these molecules are too large to shuttle into cells through the nanochannels. Construction of synthetic nanopores for the transport of large biological cargoes would be a step forward. De novo design using DNA nanotechnology gives high structural precision and programmability, dynamic nano-mechanical control and extensive chemical modifications. In this project I will develop the first mechanically-adaptable nanopores for size-selective biomolecule transport across cell membrane by uniquely combining DNA origami nanotechnology, machine-inspired design and synthetic biology.
Expertise
Publicaties
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2024
Compliant DNA Origami Nanoactuators as Size-Selective Nanopores
Ze Yu / Anna V. Baptist / Susanne C.M. Reinhardt / Eva Bertosin / Cees Dekker / Ralf Jungmann / Amelie Heuer-Jungemann / Sabina Caneva
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2024
Hexagonal Boron Nitride Spacers for Fluorescence Imaging of Biomolecules
Xiliang Yang / Dong Hoon Shin / Ze Yu / Kenji Watanabe / Takashi Taniguchi / Vitaliy Babenko / Stephan Hofmann / Sabina Caneva
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2024
Site-Specific Integration of Hexagonal Boron Nitride Quantum Emitters on 2D DNA Origami Nanopores
Yabin Wang / Ze Yu / Carlas S. Smith / Sabina Caneva
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Nevenwerkzaamheden
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2024-06-01 - 2025-05-31