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The ability of a cell to separate its own matter from its surroundings is a basic requirement for life. A team of researchers at AMOLF and Delft University of Technology have managed to create a synthetic container, or lipid vesicle, that is able to hold a range of different biological systems: from a cytoskeleton to entire E.coli bacteria. Their findings on this optimized cDICE method, which has the potential to reveal the inner workings of life, are published in ACS Synthetic Biology on DATE.

Medieval knights either had thick, cumbersome armour, or they could wear less protective armour and be flexible in combat – they couldn’t have both. Cells, on the other hand, do have it all. Researchers from Delft University of Technology (TU Delft), Leeds University, Institut Fresnel in Marseille, and Institut Curie in Paris discovered that proteins called ‘septins’ reinforce the fragile membrane of a cell, while still being flexible enough to allow the cell to change shape.

Researchers led by Delft University of Technology (TU Delft) used 3D printing to create a novel, environmentally-friendly and living material made of algae that has many potential applications.

Researcher Chirlmin Joo of TU Delft will receive a VICI grant for developing a method to sequence proteins one at a time. He will receive 1.5 million euros from the Netherlands Organisation for Scientific Research (NWO).

In preparation for cell division, cells need to copy (‘replicate’) the DNA that they contain. A team of researchers from TU Delft, collaborating with investigators from the Francis Crick Institute in London, has now shown that the protein building blocks involved in the initial steps of DNA replication are mobile but reduce their speed at specific DNA sequences on the genome. Their findings, which will be published on 26 March in the open-access journal Nature Communications, were facilitated using an integrated approach involving biophysics and biochemistry that will propel new discoveries in the field.

The Faculty of Applied Sciences has attracted four talented international researchers through the Marie Skłodowska-Curie Actions Individual Fellowships programme of the European Union. The new Fellows are: Anders Barth (Bionanoscience), Baptiste Heiles (Imaging Physics), Josep Ingla-Aynés (Quantum Nanoscience) and José Palomo Jiménez (Chemical Engineering).

Onderzoekers van de TU Delft hebben een test ontwikkeld waarmee ze specifieke stukjes genetisch materiaal kunnen opsporen, waarna de uitslag met het blote oog af te lezen is. Met de test kunnen onder meer virussen, zoals het coronavirus, en antibioticaresistente bacteriën snel en goedkoop worden gedetecteerd. De resultaten zijn gepubliceerd in Biophysical Journal.

Researcher Marie-Eve Aubin-Tam of the Bionanoscience department has won this year's H.I. Waterman Sustainability Award. The head of the department of Bionanoscience, Marileen Dogterom, virtually presented the award to her during an online meeting on Thursday 26 November.